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Virtual Arrays is initially focused on applying
its proprietary, encoded particle technology for comprehensive
phenotypic and genotypic cellular analysis. With Virtual Arrays'
technology, researchers can perform in-parallel, complex, multiplexed,
biologically meaningful analyses in key research areas, such as
validation of drug targets, high throughput cellular screening,
assessment of new chemical entity (NCE) selectivity and specificity,
and early toxicology. Previously these analyses would require
many repetitive sequential experiments and may miss potentially
new insights into hit specificity of compound libraries. New technologies
for comprehensive cellular analysis at the molecular level are
necessary to exploit recent advances in genomics and proteomics.
Using Virtual Arrays' proprietary technology the following applications
are envisioned for pharmaceutical and basic research:
Parallel and more rapid drug development
to accelerate go/no-go decisions at an earlier stage in the research
process thereby reducing costly failures and unnecessary experiments;
Development of improved cell-based assays
with built in consistency encompassing both genetic and phenotypic
variations;
Development of multiplexed, multi-analyte
(DNA, protein and cells) detection systems;
Informatics tools that would facilitate
molecular mechanistic understanding of lead compounds and improved
decision-making.
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